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Quantitative analysis of Hedgehog gradient formation using an inducible expression system

BACKGROUND: The Hedgehog (Hh) family of secreted growth factors are morphogens that act in development to direct growth and patterning. Mutations in human Hh and other Hh pathway components have been linked to human diseases. Analysis of Hh distribution during development indicates that cholesterol...

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Detalles Bibliográficos
Autores principales: Su, Vivian F, Jones, Kelly A, Brodsky, Michael, The, Inge
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885436/
https://www.ncbi.nlm.nih.gov/pubmed/17484784
http://dx.doi.org/10.1186/1471-213X-7-43