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Rad9 modulates the P21(WAF1 )pathway by direct association with p53

BACKGROUND: Previous studies suggest that human RAD9 (hRad9), encoding a DNA damage checkpoint molecule, which is frequently amplified in epithelial tumor cells of breast, lung, head and neck cancer, participates in regulation of the tumor suppressor p53-dependent transactivation of pro-survival P21...

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Detalles Bibliográficos
Autores principales: Ishikawa, Kazuhiro, Ishii, Hideshi, Murakumo, Yoshiki, Mimori, Koshi, Kobayashi, Masahiko, Yamamoto, Ken-ichi, Mori, Masaki, Nishino, Hiroshi, Furukawa, Yusuke, Ichimura, Keiichi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885445/
https://www.ncbi.nlm.nih.gov/pubmed/17511890
http://dx.doi.org/10.1186/1471-2199-8-37