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Rad9 modulates the P21(WAF1 )pathway by direct association with p53
BACKGROUND: Previous studies suggest that human RAD9 (hRad9), encoding a DNA damage checkpoint molecule, which is frequently amplified in epithelial tumor cells of breast, lung, head and neck cancer, participates in regulation of the tumor suppressor p53-dependent transactivation of pro-survival P21...
Autores principales: | Ishikawa, Kazuhiro, Ishii, Hideshi, Murakumo, Yoshiki, Mimori, Koshi, Kobayashi, Masahiko, Yamamoto, Ken-ichi, Mori, Masaki, Nishino, Hiroshi, Furukawa, Yusuke, Ichimura, Keiichi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885445/ https://www.ncbi.nlm.nih.gov/pubmed/17511890 http://dx.doi.org/10.1186/1471-2199-8-37 |
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