Syndecan-4–dependent Rac1 regulation determines directional migration in response to the extracellular matrix

Cell migration in wound healing and disease is critically dependent on integration with the extracellular matrix, but the receptors that couple matrix topography to migratory behavior remain obscure. Using nano-engineered fibronectin surfaces and cell-derived matrices, we identify syndecan-4 as a ke...

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Detalles Bibliográficos
Autores principales: Bass, Mark D., Roach, Kirsty A., Morgan, Mark R., Mostafavi-Pour, Zohreh, Schoen, Tobias, Muramatsu, Takashi, Mayer, Ulrike, Ballestrem, Christoph, Spatz, Joachim P., Humphries, Martin J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885470/
https://www.ncbi.nlm.nih.gov/pubmed/17485492
http://dx.doi.org/10.1083/jcb.200610076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885470/
https://www.ncbi.nlm.nih.gov/pubmed/17485492
http://dx.doi.org/10.1083/jcb.200610076

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