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Syndecan-4–dependent Rac1 regulation determines directional migration in response to the extracellular matrix
Cell migration in wound healing and disease is critically dependent on integration with the extracellular matrix, but the receptors that couple matrix topography to migratory behavior remain obscure. Using nano-engineered fibronectin surfaces and cell-derived matrices, we identify syndecan-4 as a ke...
Autores principales: | Bass, Mark D., Roach, Kirsty A., Morgan, Mark R., Mostafavi-Pour, Zohreh, Schoen, Tobias, Muramatsu, Takashi, Mayer, Ulrike, Ballestrem, Christoph, Spatz, Joachim P., Humphries, Martin J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885470/ https://www.ncbi.nlm.nih.gov/pubmed/17485492 http://dx.doi.org/10.1083/jcb.200610076 |
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