The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates NEIL1 glycosylase

The checkpoint protein Rad9/Rad1/Hus1 heterotrimer (the 9-1-1 complex) is structurally similar to the proliferating cell nuclear antigen sliding clamp and has been proposed to sense DNA damage that leads to cell cycle arrest or apoptosis. Human (h) NEIL1 DNA glycosylase, an ortholog of bacterial Nei...

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Detalles Bibliográficos
Autores principales: Guan, Xin, Bai, Haibo, Shi, Guoli, Theriot, Corey A., Hazra, Tapas K., Mitra, Sankar, Lu, A-Lien
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885643/
https://www.ncbi.nlm.nih.gov/pubmed/17395641
http://dx.doi.org/10.1093/nar/gkm075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885643/
https://www.ncbi.nlm.nih.gov/pubmed/17395641
http://dx.doi.org/10.1093/nar/gkm075

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