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Base-flipping dynamics in a DNA hairpin processing reaction

Many enzymes that repair or modify bases in double-stranded DNA gain access to their substrates by base flipping. Although crystal structures provide stunning snap shots, biochemical approaches addressing the dynamics have proven difficult, particularly in complicated multi-step reactions. Here, we...

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Detalles Bibliográficos
Autores principales: Bischerour, Julien, Chalmers, Ronald
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885676/
https://www.ncbi.nlm.nih.gov/pubmed/17412704
http://dx.doi.org/10.1093/nar/gkm186