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Reduced expression of TAC1, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain

BACKGROUND: Narcolepsy causes dramatic behavioral alterations in both humans and dogs, with excessive sleepiness and cataplexy triggered by emotional stimuli. Deficiencies in the hypocretin system are well established as the origin of the condition; both from studies in humans who lack the hypocreti...

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Detalles Bibliográficos
Autores principales: Lindberg, Julia, Saetre, Peter, Nishino, Seiji, Mignot, Emmanuel, Jazin, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885801/
https://www.ncbi.nlm.nih.gov/pubmed/17521418
http://dx.doi.org/10.1186/1471-2202-8-34