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Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes
BACKGROUND: The human genome contains a large number of gene clusters with multiple-variable-first exons, including the drug-metabolizing UDP glucuronosyltransferase (UGT1) and I-branching β-1,6-N-acetylglucosaminyltransferase (GCNT2, also known as IGNT) clusters, organized in a tandem array, simila...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885805/ https://www.ncbi.nlm.nih.gov/pubmed/17475008 http://dx.doi.org/10.1186/1471-2148-7-69 |