Cargando…

Salmonella SPI1 Effector SipA Persists after Entry and Cooperates with a SPI2 Effector to Regulate Phagosome Maturation and Intracellular Replication

Salmonellae employ two type III secretion systems (T3SSs), SPI1 and SPI2, to deliver virulence effectors into mammalian cells. SPI1 effectors, including actin-binding SipA, trigger initial bacterial uptake, whereas SPI2 effectors promote subsequent replication within customized Salmonella-containing...

Descripción completa

Detalles Bibliográficos
Autores principales: Brawn, Lyndsey C., Hayward, Richard D., Koronakis, Vassilis
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885946/
https://www.ncbi.nlm.nih.gov/pubmed/18005682
http://dx.doi.org/10.1016/j.chom.2007.02.001