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WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells

The Wiskott-Aldrich Syndrome protein (WASP) is an adaptor protein that is essential for podosome formation in hematopoietic cells [1]. Given that 80% of identified Wiskott-Aldrich Syndrome patients result from mutations in the binding site for WASP-interacting-protein (WIP) [2], we examined the poss...

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Detalles Bibliográficos
Autores principales: Chou, Hsiu-Chuan, Antón, Inés M., Holt, Mark R., Curcio, Claudia, Lanzardo, Stefania, Worth, Austen, Burns, Siobhan, Thrasher, Adrian J., Jones, Gareth E., Calle, Yolanda
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885947/
https://www.ncbi.nlm.nih.gov/pubmed/17141616
http://dx.doi.org/10.1016/j.cub.2006.10.037