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WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells
The Wiskott-Aldrich Syndrome protein (WASP) is an adaptor protein that is essential for podosome formation in hematopoietic cells [1]. Given that 80% of identified Wiskott-Aldrich Syndrome patients result from mutations in the binding site for WASP-interacting-protein (WIP) [2], we examined the poss...
Autores principales: | Chou, Hsiu-Chuan, Antón, Inés M., Holt, Mark R., Curcio, Claudia, Lanzardo, Stefania, Worth, Austen, Burns, Siobhan, Thrasher, Adrian J., Jones, Gareth E., Calle, Yolanda |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885947/ https://www.ncbi.nlm.nih.gov/pubmed/17141616 http://dx.doi.org/10.1016/j.cub.2006.10.037 |
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