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PtdIns(3,4,5)P(3)-Dependent and -Independent Roles for PTEN in the Control of Cell Migration
BACKGROUND: Phosphatase and tensin homolog (PTEN) mediates many of its effects on proliferation, growth, survival, and migration through its PtdIns(3,4,5)P(3) lipid phosphatase activity, suppressing phosphoinositide 3-kinase (PI3K)-dependent signaling pathways. PTEN also possesses a protein phosphat...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885949/ https://www.ncbi.nlm.nih.gov/pubmed/17240336 http://dx.doi.org/10.1016/j.cub.2006.12.026 |