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PtdIns(3,4,5)P(3)-Dependent and -Independent Roles for PTEN in the Control of Cell Migration

BACKGROUND: Phosphatase and tensin homolog (PTEN) mediates many of its effects on proliferation, growth, survival, and migration through its PtdIns(3,4,5)P(3) lipid phosphatase activity, suppressing phosphoinositide 3-kinase (PI3K)-dependent signaling pathways. PTEN also possesses a protein phosphat...

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Detalles Bibliográficos
Autores principales:	Leslie, Nick R., Yang, Xuesong, Downes, C. Peter, Weijer, Cornelis J.
Formato:	Texto
Lenguaje:	English
Publicado:	Cell Press 2007
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885949/ https://www.ncbi.nlm.nih.gov/pubmed/17240336 http://dx.doi.org/10.1016/j.cub.2006.12.026

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