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Glycoprotein Structural Genomics: Solving the Glycosylation Problem
Glycoproteins present special problems for structural genomic analysis because they often require glycosylation in order to fold correctly, whereas their chemical and conformational heterogeneity generally inhibits crystallization. We show that the “glycosylation problem” can be solved by expressing...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885966/ https://www.ncbi.nlm.nih.gov/pubmed/17355862 http://dx.doi.org/10.1016/j.str.2007.01.011 |