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Glycoprotein Structural Genomics: Solving the Glycosylation Problem

Glycoproteins present special problems for structural genomic analysis because they often require glycosylation in order to fold correctly, whereas their chemical and conformational heterogeneity generally inhibits crystallization. We show that the “glycosylation problem” can be solved by expressing...

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Detalles Bibliográficos
Autores principales: Chang, Veronica T., Crispin, Max, Aricescu, A. Radu, Harvey, David J., Nettleship, Joanne E., Fennelly, Janet A., Yu, Chao, Boles, Kent S., Evans, Edward J., Stuart, David I., Dwek, Raymond A., Jones, E. Yvonne, Owens, Raymond J., Davis, Simon J.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885966/
https://www.ncbi.nlm.nih.gov/pubmed/17355862
http://dx.doi.org/10.1016/j.str.2007.01.011