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Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1

BACKGROUND: The Myc oncoprotein is a transcriptional regulator whose function is essential for normal development. Myc is capable of binding to 10% of the mammalian genome, and it is unclear how a developing embryo controls the DNA binding of its abundant Myc proteins in order to avoid Myc's po...

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Detalles Bibliográficos
Autores principales: Goodliffe, Julie M, Cole, Michael D, Wieschaus, Eric
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887537/
https://www.ncbi.nlm.nih.gov/pubmed/17519021
http://dx.doi.org/10.1186/1471-2199-8-40