The Gtpase Rho Controls a P53-Dependent Survival Checkpoint during Thymopoiesis

During the early stages of thymopoiesis, cell survival is controlled by cytokines that regulate the expression of antiapoptotic proteins such as Bcl-2. At the pre-T cell stage, a critical checkpoint for β chain selection is monitored by the tumor suppressor p53: pre-T cells can survive and different...

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Detalles Bibliográficos
Autores principales: Costello, Patrick S., Cleverley, Steve C., Galandrini, Ricciarda, Henning, Stefan W., Cantrell, Doreen A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887705/
https://www.ncbi.nlm.nih.gov/pubmed/10880528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887705/
https://www.ncbi.nlm.nih.gov/pubmed/10880528

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