Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies

Human B cells that coexpress surrogate and conventional light chains (V-preB(+)L(+)) show an unusual heavy and light chain antibody repertoire that display evidence of receptor editing. However, it is unclear whether V-preB(+)L(+) B cells have been silenced by receptor editing or still express autor...

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Detalles Bibliográficos
Autores principales: Meffre, Eric, Schaefer, Anne, Wardemann, Hedda, Wilson, Patrick, Davis, Eric, Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887722/
https://www.ncbi.nlm.nih.gov/pubmed/14699083
http://dx.doi.org/10.1084/jem.20031550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887722/
https://www.ncbi.nlm.nih.gov/pubmed/14699083
http://dx.doi.org/10.1084/jem.20031550

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