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Regulation of an Inwardly Rectifying ATP-sensitive K(+) Channel in the Basolateral Membrane of Renal Proximal Tubule

Functional coupling of Na(+),K(+)-ATPase pump activity to a basolateral membrane (BLM) K(+) conductance is crucial for sustaining transport in the proximal tubule. Apical sodium entry stimulates pump activity, lowering cytosolic [ATP], which in turn disinhibits ATP-sensitive K(+) (K(ATP)) channels....

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Detalles Bibliográficos
Autores principales: Mauerer, Ulrich R., Boulpaep, Emile L., Segal, Alan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887764/
https://www.ncbi.nlm.nih.gov/pubmed/9417142