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The Lipid–Protein Interface of aShaker K(+) Channel

Tryptophan-substitution mutagenesis was applied to the first and third transmembrane segments (S1 and S3) of a Shaker-type K(+) channel for the purpose of ascertaining whether these sequences are α-helical. Point mutants were examined for significant functional changes, indicated by the voltage-acti...

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Detalles Bibliográficos
Autores principales: Hong, Kwang Hee, Miller, Christopher
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887780/
https://www.ncbi.nlm.nih.gov/pubmed/10613918