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Phospholipase C and myosin light chain kinase inhibition define a common step in actin regulation during cytokinesis

BACKGROUND: Phosphatidylinositol 4,5-bisphosphate (PIP(2)) is required for successful completion of cytokinesis. In addition, both PIP(2 )and phosphoinositide-specific phospholipase C (PLC) have been localized to the cleavage furrow of dividing mammalian cells. PLC hydrolyzes PIP(2 )to yield diacylg...

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Detalles Bibliográficos
Autores principales: Wong, Raymond, Fabian, Lacramioara, Forer, Arthur, Brill, Julie A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888687/
https://www.ncbi.nlm.nih.gov/pubmed/17509155
http://dx.doi.org/10.1186/1471-2121-8-15