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Phospholipase C and myosin light chain kinase inhibition define a common step in actin regulation during cytokinesis
BACKGROUND: Phosphatidylinositol 4,5-bisphosphate (PIP(2)) is required for successful completion of cytokinesis. In addition, both PIP(2 )and phosphoinositide-specific phospholipase C (PLC) have been localized to the cleavage furrow of dividing mammalian cells. PLC hydrolyzes PIP(2 )to yield diacylg...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888687/ https://www.ncbi.nlm.nih.gov/pubmed/17509155 http://dx.doi.org/10.1186/1471-2121-8-15 |