Binding induced conformational changes of proteins correlate with their intrinsic fluctuations: a case study of antibodies

BACKGROUND: How antibodies recognize and bind to antigens can not be totally explained by rigid shape and electrostatic complimentarity models. Alternatively, pre-existing equilibrium hypothesis states that the native state of an antibody is not defined by a single rigid conformation but instead wit...

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Detalles Bibliográficos
Autor principal: Keskin, Ozlem
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888692/
https://www.ncbi.nlm.nih.gov/pubmed/17509130
http://dx.doi.org/10.1186/1472-6807-7-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888692/
https://www.ncbi.nlm.nih.gov/pubmed/17509130
http://dx.doi.org/10.1186/1472-6807-7-31

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