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Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing
BACKGROUND: Previous studies of individual genes have shown that in a self-enforcing way, dimethylation at histone 3 lysine 9 (dimethyl-H3K9) and DNA methylation cooperate to maintain a repressive mode of inactive genes. Less clear is whether this cooperation is generalized in mammalian genomes, suc...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888705/ https://www.ncbi.nlm.nih.gov/pubmed/17524140 http://dx.doi.org/10.1186/1471-2164-8-131 |