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Silencing and Un-silencing of Tetracycline-Controlled Genes in Neurons

To identify the underlying reason for the controversial performance of tetracycline (Tet)-controlled regulated gene expression in mammalian neurons, we investigated each of the three components that comprise the Tet inducible systems, namely tetracyclines as inducers, tetracycline-transactivator (tT...

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Detalles Bibliográficos
Autores principales: Zhu, Peixin, Aller, M. Isabel, Baron, Udo, Cambridge, Sidney, Bausen, Melanie, Herb, Jan, Sawinski, Jürgen, Cetin, Ali, Osten, Pavel, Nelson, Mark L., Kügler, Sebastian, Seeburg, Peter H., Sprengel, Rolf, Hasan, Mazahir T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888723/
https://www.ncbi.nlm.nih.gov/pubmed/17579707
http://dx.doi.org/10.1371/journal.pone.0000533