A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain

RNA-interference-driven loss of function in specific tissues in vivo should permit analysis of gene function in temporally and spatially defined contexts. However, delivery of efficient short hairpin RNA (shRNA) to target tissues in vivo remains problematic. Here, we demonstrate that efficiency of p...

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Detalles Bibliográficos
Autores principales: Hassani, Zahra, François, Jean-Christophe, Alfama, Gladys, Dubois, Ghislaine Morvan, Paris, Mathilde, Giovannangeli, Carine, Demeneix, Barbara A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888798/
https://www.ncbi.nlm.nih.gov/pubmed/17426128
http://dx.doi.org/10.1093/nar/gkm152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888798/
https://www.ncbi.nlm.nih.gov/pubmed/17426128
http://dx.doi.org/10.1093/nar/gkm152

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