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A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain
RNA-interference-driven loss of function in specific tissues in vivo should permit analysis of gene function in temporally and spatially defined contexts. However, delivery of efficient short hairpin RNA (shRNA) to target tissues in vivo remains problematic. Here, we demonstrate that efficiency of p...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888798/ https://www.ncbi.nlm.nih.gov/pubmed/17426128 http://dx.doi.org/10.1093/nar/gkm152 |