Cargando…

Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes

Parallel tetramolecular quadruplexes may be formed with short oligodeoxynucleotides bearing a block of three or more guanines. We analyze the properties of sequence variants of parallel quadruplexes in which each guanine of the central block was systematically substituted with a different base. Twel...

Descripción completa

Detalles Bibliográficos
Autores principales: Gros, Julien, Rosu, Frédéric, Amrane, Samir, De Cian, Anne, Gabelica, Valérie, Lacroix, Laurent, Mergny, Jean-Louis
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888817/
https://www.ncbi.nlm.nih.gov/pubmed/17452368
http://dx.doi.org/10.1093/nar/gkm111