Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian In Vitro System

Secretory proteins unable to assemble into their native states in the endoplasmic reticulum (ER) are transported back or “retrotranslocated” into the cytosol for ER-associated degradation (ERAD). To examine the roles of different components in ERAD, one fluorescence-labeled ERAD substrate was encaps...

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Detalles Bibliográficos
Autores principales: Wahlman, Judit, DeMartino, George N., Skach, William R., Bulleid, Neil J., Brodsky, Jeffrey L., Johnson, Arthur E.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890003/
https://www.ncbi.nlm.nih.gov/pubmed/17540174
http://dx.doi.org/10.1016/j.cell.2007.03.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890003/
https://www.ncbi.nlm.nih.gov/pubmed/17540174
http://dx.doi.org/10.1016/j.cell.2007.03.046

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