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Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian In Vitro System
Secretory proteins unable to assemble into their native states in the endoplasmic reticulum (ER) are transported back or “retrotranslocated” into the cytosol for ER-associated degradation (ERAD). To examine the roles of different components in ERAD, one fluorescence-labeled ERAD substrate was encaps...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890003/ https://www.ncbi.nlm.nih.gov/pubmed/17540174 http://dx.doi.org/10.1016/j.cell.2007.03.046 |