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Rapid evolution of cancer/testis genes on the X chromosome

BACKGROUND: Cancer/testis (CT) genes are normally expressed only in germ cells, but can be activated in the cancer state. This unusual property, together with the finding that many CT proteins elicit an antigenic response in cancer patients, has established a role for this class of genes as targets...

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Detalles Bibliográficos
Autores principales: Stevenson, Brian J, Iseli, Christian, Panji, Sumir, Zahn-Zabal, Monique, Hide, Winston, Old, Lloyd J, Simpson, Andrew J, Jongeneel, C Victor
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890293/
https://www.ncbi.nlm.nih.gov/pubmed/17521433
http://dx.doi.org/10.1186/1471-2164-8-129