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Relating destabilizing regions to known functional sites in proteins

BACKGROUND: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relatives. Another limitation of these methods is the lack of a well annotated set of functional sites to use as benchmark for va...

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Detalles Bibliográficos
Autores principales: Dessailly, Benoît H, Lensink, Marc F, Wodak, Shoshana J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890302/
https://www.ncbi.nlm.nih.gov/pubmed/17470296
http://dx.doi.org/10.1186/1471-2105-8-141