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Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3
BACKGROUND: The endothelial cell protein C receptor (EPCR) presents protein C to the thrombin:thrombomodulin complex on the endothelium of large vessels, and enhances the generation of activated protein C (APC) and activation of protease-activated receptor-1. A previous report has demonstrated bindi...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1890847/ https://www.ncbi.nlm.nih.gov/pubmed/17459006 http://dx.doi.org/10.1111/j.1538-7836.2007.02480.x |