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Oct4 Targets Regulatory Nodes to Modulate Stem Cell Function

Stem cells are characterized by two defining features, the ability to self-renew and to differentiate into highly specialized cell types. The POU homeodomain transcription factor Oct4 (Pou5f1) is an essential mediator of the embryonic stem cell state and has been implicated in lineage specific diffe...

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Detalles Bibliográficos
Autores principales: Campbell, Pearl A., Perez-Iratxeta, Carolina, Andrade-Navarro, Miguel A., Rudnicki, Michael A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891092/
https://www.ncbi.nlm.nih.gov/pubmed/17579724
http://dx.doi.org/10.1371/journal.pone.0000553