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Oct4 Targets Regulatory Nodes to Modulate Stem Cell Function
Stem cells are characterized by two defining features, the ability to self-renew and to differentiate into highly specialized cell types. The POU homeodomain transcription factor Oct4 (Pou5f1) is an essential mediator of the embryonic stem cell state and has been implicated in lineage specific diffe...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891092/ https://www.ncbi.nlm.nih.gov/pubmed/17579724 http://dx.doi.org/10.1371/journal.pone.0000553 |