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A non-sense mutation in the putative anti-mutator gene ada/alkA of Mycobacterium tuberculosis and M. bovis isolates suggests convergent evolution

BACKGROUND: Previous studies have suggested that variations in DNA repair genes of W-Beijing strains may have led to transient mutator phenotypes which in turn may have contributed to host adaptation of this strain family. Single nucleotide polymorphism (SNP) in the DNA repair gene mutT1 was identif...

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Detalles Bibliográficos
Autores principales: Nouvel, Laurent X, Vultos, Tiago Dos, Kassa-Kelembho, Eric, Rauzier, Jean, Gicquel, Brigitte
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891112/
https://www.ncbi.nlm.nih.gov/pubmed/17506895
http://dx.doi.org/10.1186/1471-2180-7-39