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Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice

Parkinson's disease is the most common movement disorder characterized by dopaminergic dysfunction and degeneration. Loss-of-function mutations in the DJ-1 gene have been linked to autosomal recessive forms of early-onset familial Parkinson's disease. DJ-1 is thought to play roles in prote...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Hiroo, Shen, Jie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891294/
https://www.ncbi.nlm.nih.gov/pubmed/17535435
http://dx.doi.org/10.1186/1750-1326-2-10