Hexose-6-phosphate Dehydrogenase Modulates 11β-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7β-hydroxy-neurosteroids

BACKGROUND: The role of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in the regulation of energy metabolism and immune system by locally reactivating glucocorticoids has been extensively studied. Experiments determining initial rates of enzyme activity revealed that 11β-HSD1 can catalyze both...

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Detalles Bibliográficos
Autores principales: Nashev, Lyubomir G., Chandsawangbhuwana, Charlie, Balazs, Zoltan, Atanasov, Atanas G., Dick, Bernhard, Frey, Felix J., Baker, Michael E., Odermatt, Alex
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891437/
https://www.ncbi.nlm.nih.gov/pubmed/17593962
http://dx.doi.org/10.1371/journal.pone.0000561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891437/
https://www.ncbi.nlm.nih.gov/pubmed/17593962
http://dx.doi.org/10.1371/journal.pone.0000561

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