Computational screening of inhibitors for HIV-1 integrase using a receptor based pharmacophore model

The HIV (human immuno­deficiency virus) integrase has a crucial role in viral replication. Moreover, it has no cellular homologue in humans. Hence, it is considered as an attractive drug target. Many inhibitors against the integrase protein has been designed and discussed. The Y-3 inhibitor (4-acety...

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Detalles Bibliográficos
Autores principales: Jaganatharaja, Janani, Gowthaman, Ragul
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2006
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891665/
https://www.ncbi.nlm.nih.gov/pubmed/17597868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891665/
https://www.ncbi.nlm.nih.gov/pubmed/17597868

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