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On the hydrophobicity of peptides: Comparing empirical predictions of peptide log P values

Peptides are of great therapeutic potential as vaccines and drugs. Knowledge of physicochemical descriptors, including the partition coefficient logP, is useful for the development of predictive Quantitative Structure-Activity Relationships (QSARs). We have investigated the accuracy of available pro...

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Detalles Bibliográficos
Autores principales: Thompson, Sarah J, Hattotuwagama, Channa K, Holliday, John D, Flower, Darren R
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891704/
https://www.ncbi.nlm.nih.gov/pubmed/17597897