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Inactivation properties of sodium channel Na(v)1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization

BACKGROUND: Small neurons of the dorsal root ganglion (DRG) express five of the nine known voltage-gated sodium channels. Each channel has unique biophysical characteristics which determine how it contributes to the generation of action potentials (AP). To better understand how AP amplitude is maint...

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Detalles Bibliográficos
Autores principales: Patrick Harty, T, Waxman, Stephen G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892009/
https://www.ncbi.nlm.nih.gov/pubmed/17540018
http://dx.doi.org/10.1186/1744-8069-3-12