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Sensitivity of Yeast Strains with Long G-Tails to Levels of Telomere-Bound Telomerase

The Saccharomyces cerevisiae Pif1p helicase is a negative regulator of telomere length that acts by removing telomerase from chromosome ends. The catalytic subunit of yeast telomerase, Est2p, is telomere associated throughout most of the cell cycle, with peaks of association in both G1 phase (when t...

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Detalles Bibliográficos
Autores principales: Vega, Leticia R, Phillips, Jane A, Thornton, Brian R, Benanti, Jennifer A, Onigbanjo, Mutiat T, Toczyski, David P, Zakian, Virginia A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892048/
https://www.ncbi.nlm.nih.gov/pubmed/17590086
http://dx.doi.org/10.1371/journal.pgen.0030105