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PDE4 as a target in preterm labour

Cyclic nucleotide phosphodiesterases (PDE) are the enzymes catalyzing the hydrolysis and inactivation of the second messengers, cAMP and cGMP. Eleven PDE families are described to date, and selective inhibitors of some PDEs families are currently used in clinic for treating cardiovascular disorders,...

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Detalles Bibliográficos
Autores principales: Méhats, Céline, Schmitz, Thomas, Oger, Stéphanie, Hervé, Roxane, Cabrol, Dominique, Leroy, Marie-Josèphe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892053/
https://www.ncbi.nlm.nih.gov/pubmed/17570156
http://dx.doi.org/10.1186/1471-2393-7-S1-S12