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PDE4 as a target in preterm labour
Cyclic nucleotide phosphodiesterases (PDE) are the enzymes catalyzing the hydrolysis and inactivation of the second messengers, cAMP and cGMP. Eleven PDE families are described to date, and selective inhibitors of some PDEs families are currently used in clinic for treating cardiovascular disorders,...
Autores principales: | Méhats, Céline, Schmitz, Thomas, Oger, Stéphanie, Hervé, Roxane, Cabrol, Dominique, Leroy, Marie-Josèphe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892053/ https://www.ncbi.nlm.nih.gov/pubmed/17570156 http://dx.doi.org/10.1186/1471-2393-7-S1-S12 |
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