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Constrained hidden Markov models for population-based haplotyping

BACKGROUND: Haplotype Reconstruction is the problem of resolving the hidden phase information in genotype data obtained from laboratory measurements. Solving this problem is an important intermediate step in gene association studies, which seek to uncover the genetic basis of complex diseases. We pr...

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Detalles Bibliográficos
Autores principales: Landwehr, Niels, Mielikäinen, Taneli, Eronen, Lauri, Toivonen, Hannu, Mannila, Heikki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892078/
https://www.ncbi.nlm.nih.gov/pubmed/17493258
http://dx.doi.org/10.1186/1471-2105-8-S2-S9