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Constrained hidden Markov models for population-based haplotyping
BACKGROUND: Haplotype Reconstruction is the problem of resolving the hidden phase information in genotype data obtained from laboratory measurements. Solving this problem is an important intermediate step in gene association studies, which seek to uncover the genetic basis of complex diseases. We pr...
Autores principales: | Landwehr, Niels, Mielikäinen, Taneli, Eronen, Lauri, Toivonen, Hannu, Mannila, Heikki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892078/ https://www.ncbi.nlm.nih.gov/pubmed/17493258 http://dx.doi.org/10.1186/1471-2105-8-S2-S9 |
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