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Learning biophysically-motivated parameters for alpha helix prediction

BACKGROUND: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure prediction as an optimization problem, using parameterizable cost functions representing biological "pseudo-energies"....

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Detalles Bibliográficos
Autores principales: Gassend, Blaise, O'Donnell, Charles W, Thies, William, Lee, Andrew, van Dijk, Marten, Devadas, Srinivas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892091/
https://www.ncbi.nlm.nih.gov/pubmed/17570862
http://dx.doi.org/10.1186/1471-2105-8-S5-S3