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Learning biophysically-motivated parameters for alpha helix prediction
BACKGROUND: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure prediction as an optimization problem, using parameterizable cost functions representing biological "pseudo-energies"....
Autores principales: | Gassend, Blaise, O'Donnell, Charles W, Thies, William, Lee, Andrew, van Dijk, Marten, Devadas, Srinivas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892091/ https://www.ncbi.nlm.nih.gov/pubmed/17570862 http://dx.doi.org/10.1186/1471-2105-8-S5-S3 |
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