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Selection for Robustness in Mutagenized RNA Viruses

Mutational robustness is defined as the constancy of a phenotype in the face of deleterious mutations. Whether robustness can be directly favored by natural selection remains controversial. Theory and in silico experiments predict that, at high mutation rates, slow-replicating genotypes can potentia...

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Detalles Bibliográficos
Autores principales: Sanjuán, Rafael, Cuevas, José M, Furió, Victoria, Holmes, Edward C, Moya, Andrés
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892351/
https://www.ncbi.nlm.nih.gov/pubmed/17571922
http://dx.doi.org/10.1371/journal.pgen.0030093