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Selection for Robustness in Mutagenized RNA Viruses
Mutational robustness is defined as the constancy of a phenotype in the face of deleterious mutations. Whether robustness can be directly favored by natural selection remains controversial. Theory and in silico experiments predict that, at high mutation rates, slow-replicating genotypes can potentia...
Autores principales: | Sanjuán, Rafael, Cuevas, José M, Furió, Victoria, Holmes, Edward C, Moya, Andrés |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892351/ https://www.ncbi.nlm.nih.gov/pubmed/17571922 http://dx.doi.org/10.1371/journal.pgen.0030093 |
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