SELDI-TOF-MS ProteinChip array profiling of T-cell clones propagated in long-term culture identifies human profilin-1 as a potential bio-marker of immunosenescence

BACKGROUND: The adaptive immune response requires waves of T-cell clonal expansion on contact with pathogen and elimination after clearance of the source of antigen. However, lifelong persistent infections with common viruses cause chronic antigenic stimulation which takes its toll on adaptive immun...

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Detalles Bibliográficos
Autores principales: Mazzatti, Dawn J, Pawelec, Graham, Longdin, Robin, Powell, Jonathan R, Forsey, Rosalyn J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892543/
https://www.ncbi.nlm.nih.gov/pubmed/17550585
http://dx.doi.org/10.1186/1477-5956-5-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892543/
https://www.ncbi.nlm.nih.gov/pubmed/17550585
http://dx.doi.org/10.1186/1477-5956-5-7

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